HIGHLIGHTS
- who: Mengjiao Li from the (UNIVERSITY) have published the research: Enhanced trimeric ACE2 exhibits potent prophylactic and therapeutic efficacy against the SARS-CoV-2 Delta and Omicron variants in vivo, in the Journal: (JOURNAL) of 23/03/2022
- how: Next the authors evaluated the inhibitory activity of authentic Delta and Omicron variants using a microneutralization assay.
SUMMARY
Received Published online: 13 April 2022 for activity improvement, the authors generated five different trimeric ACE2 constructs (each contains an AP15 linker domain) based on these ACE2 mutations (AP15M1-AP15M5, Supplementary information, Table S2 . . .
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