Enhanced viral infectivity and reduced interferon production are associated with high pathogenicity for influenza viruses

HIGHLIGHTS

  • who: Ke Li and colleagues from the Editor: Rustom Antia, Emory University, UNITED Parkville, VIC, Australia have published the Article: Enhanced viral infectivity and reduced interferon production are associated with high pathogenicity for influenza viruses, in the Journal: (JOURNAL)
  • what: The authors develop a mathematical model of dynamics that includes the dynamics of different macrophage populations and interferon. The work provides new insight into the mechanisms that convey the observed difference in and macrophage kinetics between HP and LP infections and establishes an improved model-fitting framework to enhance the analysis of new on pathogenicity . . .

     

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