HIGHLIGHTS
- who: Ronghao Chen from the (UNIVERSITY) have published the paper: Enhancement of a prime editing system via optimal recruitment of the pioneer transcription factor P65, in the Journal: (JOURNAL) of 20/07/2022
- what: The work provides a variety of methods to work as protein scaffolds for screening target factors and thus supports further optimization of prime editing systems.
- how: These results indicated that the recruitment of P65 via Suntag system did not increase off-target prime editing. The results showed that the recruitment of P65 induced increased chromatin accessibility at the targeted . . .
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