Enhancement of cellular antioxidant-defence preserves diastolic dysfunction via regulation of both diastolic zn and ca and prevention of ryr2-leak in hyperglycemic cardiomyocytes

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  • who: Hyperglycemic Cardiomyocytes and colleagues from the Department of Biophysics, Faculty of Medicine, Ankara University, Ankara, Turkey have published the research: Enhancement of Cellular Antioxidant-Defence Preserves Diastolic Dysfunction via Regulation of Both Diastolic Zn and Ca and Prevention of RyR2-Leak in Hyperglycemic Cardiomyocytes, in the Journal: (JOURNAL) of 13/02/2014
  • what: The aim of this study was to test whether intracellular Zn2+ release besides Ca2+ release due to an increased oxidative stress/defective antioxidant defence system in cardiomyocytes under hyperglycemia mediates in part RyR2 leak and consequently diastolic dysfunction in heart from . . .

     

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