HIGHLIGHTS
- who: Tamotsu Ichiba from the (UNIVERSITY) have published the paper: Enhancement of Guanine-Nucleotide Exchange Activity of C3G for Rap1 by the Expression of Crk, CrkL, and Grb2*, in the Journal: (JOURNAL) of February/25,/1997
- what: The authors analyzed the effect of Crk, CrkL, and Grb2 on the C3G-Rap1 pathway.
SUMMARY
The authors have previously demonstrated, by using in_vivo and in_vitro systems, that C3G, which was identified as a Crk SH3 domain-binding guanine nucleotide exchange factor, specifically activates Rap1. Crk did not stimulate the guanine nucleotide exchange activity . . .
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