Enhancement of skin penetration of hydrophilic and lipophilic compounds by ph-sensitive liposomes

HIGHLIGHTS

  • who: Chaos from the Laboratory of Dermatological Physiology, Faculty of Pharmaceutical Sciences, Josai University have published the research: Enhancement of Skin Penetration of Hydrophilic and Lipophilic Compounds by pH-sensitive Liposomes, in the Journal: (JOURNAL)
  • what: This study examined the physical properties and skin penetration activities of hydrophilic and lipophilic drugs entrapped in CHEMS- and DOPE-based pH-sensitive liposomes.
  • how: The authors evaluated the skin penetration enhancement of calcein as a hydrophilic model compound and_(N-(7-nitrobenz- 2-oxa-13-diazol4yl)-PE) (NBD-PE) as a lipophilic model compound entrapped in . . .

     

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