Enhancer-promoter communication: it ’ s not just about contact

HIGHLIGHTS

  • who: Enhancer-Promoter Communication et al. from the Wellcome-MRC Cambridge Stem Cell Institute, Department of Biochemistry, University of Cambridge, Cambridge, United Kingdom have published the Article: Enhancer-Promoter Communication: It ’ s Not Just About Contact, in the Journal: (JOURNAL)
  • future: The prospect of integrating novel single-molecule imaging next-generation sequencing and chromatin modelling approaches holds great promise for the field (Itoh et_al 2021).

SUMMARY

    Particularly, enhancers appear to somehow modulate transcriptional burst frequency and cell-type-specific expression, while core promoters seemingly affecting burst size (Suter et_al, 2011; Deng . . .

     

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