Enhancing car-t cell functionality in a patient-specific manner

HIGHLIGHTS

• who: David K. Y. Zhang from the Xenograft lymphoma model Female, NODCg-Prkdcscid Il2rgtm Wjl/SzJ mice (NSG) mice, between , and , weeks of age and ~, g in weight (Jackson Laboratories), were used for in vivo therapeutic studies. Animals were maintained on, h light cycles at ambient temperature and humidity, and fed chow and water ad libitum. Procedures were approved by Harvard University`s Institutional Animal Care and Use Committee and in compliance with National Institutes of Health guidelines. Tumor inoculation and CAR-T cell treatment. NSG mice were inoculated with a high dose of , u00d7 , luciferized Raji . . .
  

   

  

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