HIGHLIGHTS
- What: This study investigates the feasibility of utilizing iterative screening rounds to identify potential drug candidates that effectively target the Notch3 R90C mutant protein associated with CADASIL. R90C , one of the most prevalent CADASIL-inducing mutations, is selected as the focus of this study. The authors focused on identifying the largest common structural feature among these molecules, which was shown in Fig 8.
- Who: Lyndia Lu from the Shanghai High School International Division, Shanghai, China have published the research work: Enhancing Drug Discovery through Iterative Screening and Advanced Computational Analysis of Notch3 R90C Mutations, in . . .
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