HIGHLIGHTS
- who: . and collaborators from the South China University of Technology have published the article: Enhancing stability of recombinant CHO cells by CRISPR/Cas9-mediated site-speci c integration into regions with distinct histone modi cations, in the Journal: (JOURNAL)
- what: Frontiersin.org 10.3389/fbioe.2022.1010719 Six gRNAs were used in this study (underlined are the PAM sequences): Vectors carrying the gRNAs, and eGFP-Cas were designed for all three integration sites.
SUMMARY
Chromosome rearrangements (Derouazi et_al, 2006; Du et_al, 2013; Bandyopadhyay et_al, 2019) or gene copy loss (Kim et_al . . .
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