Enhancing the dissolution rate of mefenamic acid with solid dispersion

HIGHLIGHTS

  • who: Asus from the Faculty of Pharmacy, Universitas Ahmad Dahlan have published the research work: Enhancing the dissolution rate of mefenamic acid with solid dispersion, in the Journal: (JOURNAL)
  • what: Preparing a solid dispersion of mefenamic acid using the carrier Avicel PH-101 with a ratio 1:1 can increase the intrinsic dissolution rate of mefenamic acid significantly compared to that of pure mefenamic acid because the interaction between mefenamic acid and Avicel PH-101 creates hydrogen_bonding instead of transforming the crystals in mefenamic acid into their amorphous state.
  • how: The test results . . .

     

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