Enhancing the effectiveness of oligonucleotide therapeutics using cell-penetrating peptide conjugation, chemical modification, and carrier-based delivery strategies

HIGHLIGHTS

  • who: Saeed Anwar et al. from the Department of Medical Genetics, Faculty of Medicine and Dentistry, University of Alberta, Edmonton, AB T G , Canada have published the Article: Enhancing the Effectiveness of Oligonucleotide Therapeutics Using Cell-Penetrating Peptide Conjugation, Chemical Modification, and Carrier-Based Delivery Strategies, in the Journal: Pharmaceutics 2023, 1130 of /2023/
  • what: For the purpose of this write-up, the discussion is limited to the classes depicted in Figure 1, which provides a simplified overview of the mechanisms employed by clinically applicable ON classes.
  • future: Research is required to optimize . . .

     

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