HIGHLIGHTS
- who: Riccardo Gamba and collaborators from the Institut Curie, PSL Research University, CNRS, UMR, Paris, France, IFOM, the FIRC Institute of have published the research: Enrichment of centromeric DNA from human cells, in the Journal: (JOURNAL)
- what: The authors show that this method can be used in combination with long-read sequencing to investigate the DNA methylation status of certain centromeres and with a specific enzyme combination also of their surrounding regions (mainly HSATII). The authors show that CenRICH facilitates single-molecule analysis of replicating centromeric fibers by DNA combing. This approach has great potential . . .
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