Enteric polymer-based amorphous solid dispersions enhance oral absorption of the weakly basic drug nintedanib via stabilization of supersaturation

HIGHLIGHTS

  • who: Yuling Qin and collaborators from the Department of Pharmacy, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China have published the Article: Enteric Polymer-Based Amorphous Solid Dispersions Enhance Oral Absorption of the Weakly Basic Drug Nintedanib via Stabilization of Supersaturation, in the Journal: Pharmaceutics 2022, 1830 of /2022/
  • what: The authors investigated the solubilization and inhibitory effects on nintedanib in the presence of polymers (HPMCAS LG HPMCAS MG Eudragit L100 55 and Eudragit L100).
  • how: These data indicated that the interac 1.0% polymer These data indicatedHowever . . .

     

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