Enteropathogenic escherichia coli uses nlea to inhibit nlrp3 inflammasome activation

HIGHLIGHTS

  • who: Hilo Yen and collaborators from the Department of Biomedical Informatics, Graduate School of Medicine, Osaka University, Osaka, Japan have published the research work: Enteropathogenic Escherichia coli Uses NleA to Inhibit NLRP3 Inflammasome Activation, in the Journal: (JOURNAL) of May/28,/2014
  • what: The authors focused on NleA because this effector has not yet been reported to be involved in the regulation of host inflammation. Because the inflammasome is increasingly being recognized as an important sensor and reactor to offending pathogens, the study showing how NleA interferes with this pathway provides important insights into efficient . . .

     

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