Enu-induced phenovariance in mice: inferences from 587 mutations

HIGHLIGHTS

  • who: N-ethyl-N-nitrosourea and collaborators from the Center for Genetics of Host Defense, UT Southwestern Medical Center, Harry Hines Boulevard, Suite NB9- D, Dallas, TX, USA have published the research work: ENU-induced phenovariance in mice: inferences from 587 mutations, in the Journal: (JOURNAL)
  • what: We estimated that 21.3% of ENU-induced missense mutations cause phenotypes detectable in typical screening assays.
  • how: To a first approximation the authors therefore infer that 21.3% of the missense alleles induced by ENU and observed among incidental mutations would be phenotypically detectable if . . .

     

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