Envelope exchange for the generation of live-attenuated arenavirus vaccines

HIGHLIGHTS

• who: Andreas Bergthaler et al. from the InstituteUniversity Hospital have published the paper: Envelope Exchange for the Generation of Live-Attenuated Arenavirus Vaccines, in the Journal: (JOURNAL)
• what: In the present report, the authors show that rLCMV/INDG has lost its pathogenic potential in mice but has retained the property of LCMVwt to induce long-lived protective CTL memory. For rLCMV-ARM*, the results were corroborated in the experiment shown in Table 3. c Number of mice that developed terminal choriomeningitis and had to be killed (according to the Swiss law for animal protection). It . . .
  

   

  

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