Enzymatic and molecular characterization of anti-leishmania molecules that differently target leishmania and mammalian eif4a proteins, lieif4a and eif4amus

HIGHLIGHTS

• who: Yosser Zina Abdelkrim et al. from the Laboratory Molecular and Experimental Pathology (LR IPT04/LR IPT04)/Laboratory and, Institut Pasteur de Tunis-University El Manar, Rue Pierre et Marie Curie, Paris, France have published the article: Enzymatic and Molecular Characterization of Anti-Leishmania Molecules That Differently Target Leishmania and Mammalian eIF4A Proteins, LieIF4A and eIF4AMus, in the Journal: Molecules 2022, 27, 5890. of /2022/
• what: This work provided further evidence that chemicals could distinctively target Leishmania and mammalian eIF4A proteins and consequently endorsed the potential of LieIF4A as a drug_target against Leishmaniases.
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