Enzymatic characterization of wild-type and mutant janus kinase 1

HIGHLIGHTS

• who: Nicholas P. D. Liau and colleagues from the Department of Medical Biology, The University of Melbourne, Royal Parade, Parkville, VIC, Australia have published the research work: Enzymatic Characterization of Wild-Type and Mutant Janus Kinase 1, in the Journal: Cancers 2019, 11, 1701 no significant differences were seen between any of the constructs (Figure 8B). of /2019/
• what: Consistent with previous studies the authors show that the presence of the pseudokinase domain leads to a dramatic decrease in enzymatic activity with no further decrease from the presence of the FERM or SH2 domains. In . . .
  

   

  

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