Enzymatic synthesis of vancomycin-modified dna

HIGHLIGHTS

• who: Chiara Figazzolo and colleagues from the Institut Pasteur, Universitu00e9 de Paris Citu00e9, CNRS, Department of Structural Biology and Chemistry, Paris, France have published the Article: Enzymatic Synthesis of Vancomycin-Modified DNA, in the Journal: Molecules 2022, 8927 of /2022/
• what: The authors report the synthesis of a modified nucleoside triphosphate equipped with a vancomycin moiety on the nucleobase. The authors demonstrate that this nucleotide analogue is suitable for polymerase-mediated synthesis of modified and importantly highlight its compatibility with the methodology. While this approach has met some success, post-SELEX modification protocols come with . . .
  

   

  

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