Epigenetic analysis in placentas from sickle cell disease patients reveals a hypermethylation profile

HIGHLIGHTS

  • who: Gislene Pereira Gil et al. from the Center for Molecular Biology and Genetic Engineering (CBMEG), University of Campinas-UNICAMP, Brazil have published the paper: Epigenetic analysis in placentas from sickle cell disease patients reveals a hypermethylation profile, in the Journal: PLOS ONE of June/22,/2021
  • what: Interestingly, in the present study, the authors identified some differentially methylated genes whose deregulation by oxidative stress has already been reported. In the present study, both HbSS and HbSC groups showed statistically significant DMPs distribution in the regions related to CpG Island with hypermethylation at CpG Island . . .

     

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