Epigenetic mechanisms underlying melanoma resistance to immune and targeted therapies

HIGHLIGHTS

  • who: Andrey Rubanov et al. from the Department of Pathology, NYU Grossman School of Medicine, New York, NY, USA have published the research work: Epigenetic Mechanisms Underlying Melanoma Resistance to Immune and Targeted Therapies, in the Journal: Cancers 2022, 14, 5858. of /2022/
  • what: The authors examine recent studies advancing the understanding of epigenetic regulation of ERVs and the emerging role of viral mimicry in overcoming melanoma immunotherapy resistance. The authors explore the role of epigenetic modulators in activating survival pathways and the contribution of phenotype switching to targeted therapy resistance.
  • how: The . . .

     

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