HIGHLIGHTS
- who: Jungeun An and Myunggon Ko from the Department of Life Sciences, Jeonbuk National University, Jeonju, Republic of Korea have published the Article: Epigenetic Modification of Cytosines in Hematopoietic Differentiation and Malignant Transformation, in the Journal: (JOURNAL)
SUMMARY
Promoter methylation can repress transcription by facilitating the formation of a transcriptional repressor complex via the recruitment of 5mC-recognizing proteins such as methyl-CpG-binding proteins (MBDs) or by directly blocking the binding 2 of 21 of transcription factors (TFs). Besides normalgenerally biology, DNA methylation dysregulated under pathological conditions, critically impacting a variety of . . .
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