Epigenetic modifications in the accumulation and function of myeloid-derived suppressor cells

HIGHLIGHTS

  • who: Liangjie Xu and colleagues from the Nanjing Drum Tower Hospital, China Jiangsu University, China have published the research: Epigenetic modifications in the accumulation and function of myeloid-derived suppressor cells, in the Journal: (JOURNAL)

SUMMARY

    MDSCs inhibit the immune_response by suppressing the proliferation of pro-inflammatory T_cells and B cells, induce apoptosis and block proinflammatory cytokine expression in activated cells. frontiersin.org 10.3389/fimmu.2022.1016870 and let-7e) are enriched in correlation with myeloid cell accrual and contribute to the immunotherapy resistance in melanoma patients. Immune suppression is the main . . .

     

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