HIGHLIGHTS
- who: Arnaud Carrier from the (UNIVERSITY) have published the Article: Epigenetically regulated, in the Journal: (JOURNAL)
- what: The authors show that PCDHB15, a member of this cluster of genes, marks melanoma aggressiveness and plays a functional role in regulating the hallmarks of cancerogenesis. Among them, the authors focused the analysis on PCDHB15, which belongs to the protocadherin beta family cluster located on chromosome 5 (5q31.3). The authors demonstrate an epigenetic regulation of the expression of the PCDHB15 gene in melanoma cell lines. In accordance with findings in other cancers, the authors propose that the . . .
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