HIGHLIGHTS
- who: Mahsa Alemrajabi from the Department of Physics, Florida Atlantic University, Boca Raton, FL, USA have published the Article: Epistasis-Driven Evolution of the SARS-CoV-2 Secondary Structure, in the Journal: (JOURNAL) of April/13,/2022
- what: Last the authors show that WC sites under the strongest epistatic constraint reside in a three-stemmed pseudoknot motif that plays an essential role in programmed ribosomal frameshifting whereas those under the weakest epistatic constraint are located in 3` UTR motifs that regulate viral replication and pathogenicity. Specifically, the authors examine several characteristics of derived alleles produced . . .
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