Epithelial expression of human abo blood group genes is dependent upon a downstream regulatory element functioning through an epithelial cell-specific transcription factor, elf5*

HIGHLIGHTS

  • who: Rie Sano from the Identification of an Epithelial Cell-specific Regulatory Element Downstream of the ABO Gene-Publicly available data of Open Chromatin by DNaseI HS from ENCODE/OpenChrom (Duke University) ENCODE July , Freeze (26) from the UCSC genome browser on human February , (GRCh37/ hg19) assembly showed genome-wide maps for DHSs in epithelial cells including pHTE, HPDE6-E, and , (Fig1), where there were many DHSs located around ⫺0.1, ⫹5.8, ⫹22.6, and ⫹36., kb from the ATG translation start site of exon , of ABO. Fig. , also shows DHSs in , cells representative of erythroid . . .

     

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