HIGHLIGHTS
- who: Top from the Experimental and Molecular Pathology, Institute of Pathology, Ludwig-Maximilians-Universität München, Munich, Germany have published the research work: epithelial transition: a possible link to tumor suppression by, in the Journal: (JOURNAL)
- what: The authors show that p53 directly induces CST5 expression by binding to a p53 response element upstream of the CST5 promoter. The authors demonstrate that SNAIL directly represses CST5 expression and that calcitriol treatment reverses this effect. p53 induces CST5 expression
- how: The authors identified several E-boxes upstream of the CST5 promoter and could . . .
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