Epsilon toxin from clostridium perfringens causes inhibition of potassium inward rectifier (kir) channels in oligodendrocytes

HIGHLIGHTS

  • who: Jean Louis Bossu and collaborators from the Institut des Neurosciences Cellulaires et Intégratives, (INCI)-CNRS, UPR , Strasbourg, France have published the article: Epsilon Toxin from Clostridium perfringens Causes Inhibition of Potassium inward Rectifier (Kir) Channels in Oligodendrocytes, in the Journal: (JOURNAL)
  • what: Using primary cultures, the authors demonstrate that the application of ETX induces a small transmembrane depolarization and inhibition of a fraction of Kir transmembrane current. The authors report several observations revealing new ETX actions on rat oligodendrocytes in primary cerebellar cultures. (i) ETX induces small but significant RMP depolarization (by +6 . . .

     

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