Eqtls as causal instruments for the reconstruction of hormone linked gene networks

HIGHLIGHTS

• who: Sean Bankier from the University of California, Irvine, United States have published the paper: eQTLs as causal instruments for the reconstruction of hormone linked gene networks, in the Journal: (JOURNAL)
• what: This approach has offered many new opportunities in endocrinology , where hormonal networks are well understood and hence lend themselves to informed mapping approaches. The authors describe how causal inference methods have been used to overcome some of the limitations of GWAS and how these can be integrated for the reconstruction of causal molecular networks by using eQTLs as genetic instruments. Through an extension . . .
  

   

  

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