Er-pm junctions on gabaergic interneurons are organized by neuregulin 2/vap interactions and regulated by nmda receptors

HIGHLIGHTS

• who: Detlef Vullhorst and colleagues from the Development, Bethesda, MD, USA have published the article: ER-PM Junctions on GABAergic Interneurons Are Organized by Neuregulin 2/VAP Interactions and Regulated by NMDA Receptors, in the Journal: (JOURNAL)
• what: The authors elucidate the mechanistic basis of proNRG2 clustering at junctions and its regulation by NMDA Importantly the authors demonstrate that proNRG2 promotes the formation of junctions by directly binding the ER-resident membrane tether like Based on these and prior studies the authors propose that proNRG2 and serve as co-regulated downstream effectors of NMDA to . . .
  

   

  

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