Erf3a nonsense_mutations by promoting premature termination codon readthrough

HIGHLIGHTS

  • who: Small-molecule eRF and collaborators from the Department University of Chapel Hill, North Carolina, USA have published the research: eRF3a nonsense_mutations by promoting premature termination codon readthrough, in the Journal: (JOURNAL) of July/13,/2021
  • what: The authors propose that this method could be applied to rare-genotype HBECs and HNECs as they become available to create the cellular resources required for personalized medicine and drug discovery. The authors directly compared the functional response of patient-derived Bmi-1/hTERT_cell lines and the primary cells from which they were developed. By testing a Trikafta . . .

     

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