Erythrocytes possess an intrinsic barrier to nitric oxide consumption*

HIGHLIGHTS

  • who: Mark W. Vaughn from the (UNIVERSITY) have published the Article: Erythrocytes Possess an Intrinsic Barrier to Nitric Oxide Consumption*, in the Journal: (JOURNAL) of April/16,/1999
  • what: The authors reason that their data may also represent an intrinsic limitation in RBC consumption of NO.
  • how: To accomplish this the authors designed an experiment that exploited the competition for NO between RBC and extracellular Hb. To avoid these limitations the authors designed the following competition approach. The authors used spermine NONOate as an NO donor which does not enter RBC at an . . .

     

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