Essential phospholipids decrease apoptosis and increase membrane transport in human hepatocyte cell lines

HIGHLIGHTS

• who: Dominik Wupperfeld from the (UNIVERSITY) have published the research: Essential phospholipids decrease apoptosis and increase membrane transport in human hepatocyte cell lines, in the Journal: EPL (0.25 mg/ml), and PPC (both concentrations), but not by PI. The PLs had no effects on HepaRG cell BSEP activity.
• what: Analyses of hepatocyte transport function BCRP Intracellular accumulation of the model substrate, mitoxantrone, was used to assess the activity of BCRP in cell culture, i.e., decreased intracellular concentrations of mitoxantrone indicate increased activity of BCRP in the extracellular transport of this substrate.
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