Establishing a blueprint for ced-3-dependent killing through identification of multiple substrates for this protease*

HIGHLIGHTS

• who: Rebecca C. Taylor from the (UNIVERSITY) have published the Article: Establishing a Blueprint for CED-3-dependent Killing through Identification of Multiple Substrates for This Protease*, in the Journal: (JOURNAL) of May/18,/2007

SUMMARY

Caspases are present in most cells as inactive proenzymes and become activated during apoptosis through diverse signaling pathways. In several cases, this led directly to the discovery of a role for their mammalian counterparts in the regulation of apoptosis, the caspases being a notable example. The worm caspase, CED-3, has been established as essential for the . . .

 



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