Establishment and genetic characterization of cell lines derived from proliferating nasal polyps and sinonasal inverted papillomas

HIGHLIGHTS

  • who: Thawaree Nukpook from the DepartmentKaen University have published the research: Establishment and genetic characterization of cell lines derived from proliferating nasal polyps and sinonasal inverted papillomas, in the Journal: Scientific Reports Scientific Reports

SUMMARY

    For the immortalization of normal human epithelial_cells, both inactivation of the p16INK4A/pRB pathway and telomerase activation are ­required24. Demonstrated that the NP2, NP2/K4DT, NP3, NP3/T, IP4, and IP4/K4DT_cells had human male karyotypes. In NP2/K4DT_cells, there was a partial deletion of chromosome number 6 in 58% (29/50) of the cell populations. In NP3 . . .

     

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