HIGHLIGHTS
SUMMARY
Prognostic model was developed for facilitating personalized PAAD treatment. Glutamine and asparagine are two key nutrients affecting pancreatic cancer cell development, moreover, these two are one of the bases of protein synthesis in pancreatic cancer cells to promote resistance to oxidative stress and are essential for pancreatic cancer cell growth and proliferation. Consistent clustering screened stable molecular subtypes utilizing genes of oxidative stress pathway. The authors downloaded transcriptomic data of samples from the pancreatic cancer-Australia (PACA-AU) and pancreatic cancerCanada (PACA-CA) cohorts in the International Cancer Genome Consortium (ICGC) database (https://dcc . . .
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