Establishment of anti-dkk3 peptide for the cancer control in head and neck squamous cell carcinoma (hnscc)

HIGHLIGHTS

  • who: Naoki Katase from the Department of Oral Pathology, Graduate School of Biomedical Sciences, Nagasaki University, u20117u2011, Sakamoto, Nagasaki, Nagasaki, u20118588, Japan have published the article: Establishment of anti-DKK3 peptide for the cancer control in head and neck squamous cell carcinoma (HNSCC), in the Journal: (JOURNAL)
  • what: The authors generated deletion mutants of DKK3 expression plasmids that enables the expression of DKK3 lacking CRD1 (DKK3u0394C1), CRD2 (DKK3u0394C2), or both CRD1 and CRD2 (DKK3u0394C1u0394C2), and evaluated its effects on cellular proliferation, migration, and invasion. The authors identified the functional domain of DKK3.
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