Estimating the fitness cost of escape from hla presentation in hiv-1 protease and reverse transcriptase

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  • who: Transcriptase and colleagues from the Institute for Integrative Biology, ETH Zurich, Zurich, Switzerland, Department of Ecology and Evolutionary Biology, Princeton University, Princeton, New Jersey, United have published the Article: Estimating the Fitness Cost of Escape from HLA Presentation in HIV-1 Protease and Reverse Transcriptase, in the Journal: (JOURNAL) of May/24,/2012
  • what: The authors assess the replicative cost of mutations which are likely to escape presentation by HLA molecules in the region of HIV-1 protease and reverse Specifically the authors combine computational approaches for prediction of in vitro replicative fitness and . . .

     

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