Estrogen acts through estrogen receptor-β to promote mannan-induced psoriasis-like skin inflammation

HIGHLIGHTS

• who: Huimei Wu from the Southern Medical University, Karolinska Institute United Medical Center, School of Pharmaceutical Sciences, Technology, Shenzhen, China have published the research: Estrogen Acts Through Estrogen Receptor-u03b2 to Promote Mannan-Induced Psoriasis-Like Skin Inflammation, in the Journal: (JOURNAL)
• what: This model showed a clear female preponderance in disease development and can be induced in different common mouse strains by epicutaneous applications of mannan, a natural route of antigen encounter in the skin. The role of estrogen in psoriasis is often considered to be controversial and here the authors report a disease . . .
  

   

  

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