Estrogen receptor positive breast cancers have patient specific hormone sensitivities and rely on progesterone receptor

HIGHLIGHTS

• who: Valentina Scabia from the Institut Fu00e9du00e9rale de Lausanne, Lausanne, SwitzerlandLausanne University have published the Article: Estrogen receptor positive breast cancers have patient specific hormone sensitivities and rely on progesterone receptor, in the Journal: NATURE COMMUNICATIONS NATURE COMMUNICATIONS
• what: The authors show patient-specific responses of ER + BC cells to physiologically relevant levels of E2 and progesterone (P4) and dissect the role of PR genetically in_vivo. The authors provide new insights into the respective contributions of the two major ovarian hormones, E2 and P4, using highly disease-relevant models.

SUMMARY

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