Etiology of end-stage liver cirrhosis impacts hepatic natural killer cell heterogenicity

HIGHLIGHTS

  • who: Ana C. Maretti-Mira from the Medicine, Japan Osaka University, Japan have published the research work: Etiology of end-stage liver cirrhosis impacts hepatic natural killer cell heterogenicity, in the Journal: (JOURNAL)
  • what: The authors propose that hepatic NK cell population heterogeneity is directly correlated to the cause of cirrhosis. The authors show that, in advanced NASH, cNK cells behave as pro-inflammatory cells.

SUMMARY

    In the liver, the hepatic NK (He-NK) cell population comprises resident NK (rNK) cells, mainly cytokine secretors, and infiltrating conventional circulating NK (cNK) cells . . .

     

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