Eupalinolide j inhibits cancer metastasis by promoting stat3 ubiquitin-dependent degradation

HIGHLIGHTS

  • who: Hongtao Hu and colleagues from the School of Pharmaceutical Sciences, Zhejiang Chinese Medical University, Hangzhou, China have published the research: Eupalinolide J Inhibits Cancer Metastasis by Promoting STAT3 Ubiquitin-Dependent Degradation, in the Journal: Molecules 2023, 28, 3143. of 12/03/2022
  • what: A sesquiterpene lactone component EJ was selected from Traditional Chinese Medicine EL, which has anti-tumor metastasis effects both in_vitro and in_vivo and no obvious toxicity at the therapeutic concentrations in both environments.
  • how: The results showed that EJ below 4 of 12 5 u00b5M was not significantly cytotoxic . . .

     

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