Eva1a regulates hematopoietic stem cell regeneration via er-mitochondria mediated apoptosis

HIGHLIGHTS

• who: Bo Liu from the Eva1aflox/flox (hereafter referred to as Eva1aF/F) mice were kindly provided by DrChen Yingyu [14]. To obtain tissue-specific or inducible Eva1a knockout mice, the Eva1aF/F mice were crossed with Vav-Cre, Mx-Cre and ERT-Cre transgenic mice. Chop knockout mice was used as described previously [16]., .SJL-PtprcaPep3b/Boy (CD45.1) mice or CD45.1/CD45., heterozygous mice were used as recipients or competitors for HSCs transplantation [31]. All of these strains were maintained in a C BL/, background and were housed in a specific pathogen-free environment . . .
  

   

  

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