Evaluate the immune-related erna models and signature score to predict the response to immunotherapy in thyroid carcinoma

HIGHLIGHTS

SUMMARY

    In contrast, tumor suppressors can also induce eRNAs to suppress tumors. eRNAs have emerged as important regulators of the immune_response, and played a central role in controlling immune-related functions. Gene Set Enrichment Analysis (GSEA) was performed to analyze the difference of the immune_response between different risk groups using GSEA 4.1.0. The result of GO functional analysis suggested that the DEGs were mainly enriched in humoral immune_response, immunoglobulin complex, and antigen binding (Fig 9A). GSEA indicated that humoral immune_response, regulation of humoral immune_response, and positive regulation of humoral immune_response were significantly involved . . .

     

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