Evaluating targeted therapies in ovarian cancer metabolism: novel role for pcsk9 and second generation mtor inhibitors

HIGHLIGHTS

  • who: Dafne Jacome Sanz and colleagues from the Laboratory of Immunoregulation, Faculty of Medicine and Health Technology, Tampere University, Ltd, Tampere University Hospital, Tampere, Finland have published the article: Evaluating Targeted Therapies in Ovarian Cancer Metabolism: Novel Role for PCSK9 and Second Generation mTOR Inhibitors, in the Journal: (JOURNAL)
  • what: The authors aimed to investigate the therapeutic value of targeting lipid in OC. The authors investigated the role of PCSK9, the proprotein convertase subtilisin/kexin type-9 regulating cholesterol and lipid metabolism, in OC cell survival and its intracellular signaling, in cell lines (n=8 . . .

     

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