Evaluating the efficacy and mechanism of metformin targets on reducing alzheimer’s disease risk in the general population: a mendelian randomisation study

HIGHLIGHTS

  • who: Jie Zheng from the (UNIVERSITY) have published the article: Evaluating the efficacy and mechanism of metformin targets on reducing Alzheimeru2019s disease risk in the general population: a Mendelian randomisation study, in the Journal: (JOURNAL)
  • what: This study reports findings based on the STROBE-MR guidelines (ESM Method 4) , testing the three MR assumptions using the following approaches.
  • how: The most statistically powerful eQTL dataset was obtained in brain cortex in which gene_expression levels of 6601 brain donors were measured . Given the limited number of predictors for each gene the authors applied the . . .

     

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