Evaluation of analogs of mutacin 1140 in systemic and cutaneous methicillin-resistant staphylococcus aureus infection models in mice

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  • who: ufeffMinufeff ufeffJuufeff and colleagues from the South Valley University, Iran have published the paper: Evaluation of analogs of mutacin 1140 in systemic and cutaneous methicillin-resistant ufeffStaphylococcus aureusufeff infection models in mice, in the Journal: (JOURNAL)
  • what: The authors further expanded the systemic MRSA infection study to compare the activity of the combined K2A:R13A analogs to native Mu1140 and vancomycin. These observations support the need to further preclinical studies using K2A:R13, in particular pharmacotoxicity studies aimed at optimizing the i.v. dosing regimen of the Mu1140 analogs and preclinical safety studies. It . . .

     

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