Evaluation of autophagy inducers in epithelial cells carrying the ύf508 mutation of the cystic fibrosis transmembrane conductance regulator cftr

HIGHLIGHTS

  • who: Shaoyi Zhang from the (UNIVERSITY) have published the research work: Evaluation of autophagy inducers in epithelial cells carrying the ΎF508 mutation of the cystic fibrosis transmembrane conductance regulator CFTR, in the Journal: (JOURNAL)
  • what: If the authors compare the relative increase of GFP-LC3 dots number induced by treatment (cysteamine/EGCG)over untreated controls, it appears that the relative increase is similar in 16 HBE cells and CFBE cells. The authors attempted to identify autophagy inducers that might interact with cysteamine to replace EGCG by another compound that would be either more efficient or . . .

     

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