Evaluation of bisphenylthiazoles as a promising class for combating multidrug-resistant fungal infections

HIGHLIGHTS

  • who: Mohamed Hagras and collaborators from the Department Pharmaceutical Organic Chemistry, College Pharmacy, Al-Azhar University, Cairo have published the Article: Evaluation of bisphenylthiazoles as a promising class for combating multidrug-resistant fungal infections, in the Journal: PLOS ONE of 13/Oct/2020
  • what: The authors aimed to maximize the antifungal potency of bisphenylthiazoles by studying the structure-activity relationships (SAR) at oxadiazole position-2.
  • how: Interestingly the authors found that this derivative exhibited dual antibacterial and antifungal activity (Fig 1) and the authors hypothesized that this mixed activity is due to the . . .

     

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